LRIG New England Chapter





LRIG New England and the Boston LIMS / LI group present a discussion on

Laboratory Informatics

Sponsored by:

  

  • February 10th, 2010                            
    Millennium: The Takeda Oncology Company 
    35 Landsdowne St
    Cambridge, MA 02139

REGISTER HERE

 


AGENDA:

5:00pm Social Hour with appetizers and drinks
6:00pm Opening Statements

6:10pm

ELN Expert Panel: Strategies for Both R&D and QC

Moderated by: April Ciampoli Fowke of Amgen
Panelists: Debra Igo of Novartis, Mike Stroz of AstraZeneca, Craig Tulig of Millennium

7:10pm Research Gateway: Amgen’s Integration Platform for Discovery Data
Bill Goode, Amgen Inc.
7:40pm SiLA Introduction and Overview
Dieter Speidel, Standardisation in Lab Automation (SiLA)


Abstracts & Bios:

ELN Expert Panel: Strategies for Both R&D and QC

Electronic Laboratory Notebooks (ELNs) have been used in practice for many years now in Pharmaceutical and Biotech R&D.  ELN technologies have proven to be a valuable asset for these organizations but can be challenging to implement effectively.  This will be a panel discussion with industry experts on ELN technologies, their implementation and strategies for maximizing value.

MODERATOR

April Ciampoli Fowke
Amgen Inc.

April has worked in the biotech industry for over 13 years as a project manager, business analyst and process engineer. In her current role at Amgen, April serves as a project manager and business analyst in the Research Informatics department focusing on delivering integrated informatics solutions that allow for optimizing the drug discovery process. Prior to joining Amgen; April worked at ArQule, Inc. for more than 9 years delivering automated hardware and informatics systems and processes for the high-throughput combinatorial chemistry automated technology platform. April obtained a B.S. in Chemical Engineering at the University of Massachusetts, Amherst, MA in 1996 and a M.S. in Chemical Engineering at Northeastern University in 2005

PANELISTS

Debra Igo
NIBR Information Technology and Automation Services
Novartis Institutes for BioMedical Research, Inc.

Michael Stroz
AstraZeneca

Michael Stroz is currently the Global QC Systems owner and leads AstraZeneca’s global projects to deploy LIMS, and eLab across the operations sites.  Mike’s group in Global Operations IS is responsible for the project management, and configuration of these systems.  Prior to his current role, he was the QC Director at AstraZeneca’s Westborough manufacturing location and was responsible for the development and deployment of the local QC Systems including LIMS, eLab and CDS systems.

Mike is an Analytical Chemist from the University of Pittsburgh with 19 years of experience in the Pharmaceutical industry in the areas of informatics, analytical chemistry, and laboratory automation.  He has worked in Analytical Development R&D and Operations QA and QC

Craig Tulig
Associate Director
R&D Systems
Millennium: The Takeda Oncology Company 

Craig has been with Millennium for over 10 years and is responsible for Millennium’s “Drug Discovery Systems”, which includes areas such as Drug Discovery Decision Support, Chemistry Systems, BioAssay Data Capture, and Workflow/Logistics. Craig first started working with Chemistry eNotebooks in 2003 and led the design and deployment of a system that seamlessly integrated commonly used Chemistry Lab Systems, such as Reagent Inventory, Reagent Catalogs, Structure to Name, and Compound Registration. More recently, Millennium has started the deployment of a Discovery-wide eNotebook with drivers including preparation for the nomination of Development Candidates and Technical Reports ultimately used for IND filings.

 

Research Gateway: Amgen’s Integration Platform for Discovery Data
Bill Goode
Project Manager
Amgen Inc.

It is critical for research project teams in Pharmaceutical Discovery organizations to be able to make decisions using all relevant research data.  Given how R&D information systems are typically introduced and evolve organically, this is no trivial task.  This presentation will examine the challenges and strategies for integrating disparate IS data sources using Amgen's Research Gateway platform as a case study.  Research Gateway is Amgen's integration platform and query tool for integrating Discovery Research data which uses SOA and other technologies.

Biography

Bill started his career at Millennium Pharmaceuticals after graduating from Worcester Polytechnic Institute in 1998.  At Millennium he worked within the Lead Discovery group building automation and IT systems for Compound Management, High Throughput Screening, and Molecular Pharmacology.  In 2003, Bill joined Novartis as head of the Robotics & Automation group in Cambridge, MA.  Bill currently works at Amgen within the Research Informatics department as a project manager leading enterprise software projects.  At Amgen he has managed global teams to deliver information systems for HTS & Therapeutic Area data analysis, Small Molecule Inventory, in addition to Research Gateway.

 

SiLA Introduction and Overview
Dieter Speidel
CTO
Standardisation in Lab Automation (SiLA)

Pharma companies are under growing pressure to integrate automated systems for new applications in shorter time and to be able to adopt technological innovations provided by instrument suppliers more easily and rapidly. However, they are restricted in their flexibility of choosing specific instruments to make use of technological innovations provided by instrument suppliers in the extent they would like to. Furthermore, adaptation of hardware and software to new workflow requirements is too time consuming.

The new SiLA standard shall allow flexible and easy integration and replacement of instruments in automated lab systems. The SiLA standard is based on the concept of Common Command Sets for instrument control and data exchange. The standard shall define a Common Command Set for each Device Class used in an automated lab system and provide guidelines for Specific Commands provided by the instrument supplier for extended functionality

Biography

Dieter is an experienced entrepreneur with strong life science / IVD LAB AUTOMATION industry experience (>20 YEARS).  As a business developer, initiator, consultant and networker he has a track record in the initiation and management of not-for-profit industry associations in the life science lab automation industry. Dieter is the co-founder and executive board member of the Swiss industry cluster and competence center Toolpoint for Life Science (www.toolpoint.ch).  He is the co-founder, executive board member and CTO of the global SiLA association for Standardisation in Lab Automation.