Assay Development & Screening and Compound Profiling Automation Department

 

                                                                                                                                                                                            
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   LRIG Southeast Chapter

LRIG SouthEast Presentations

 

June 7, 1999 LRIG SouthEast Chapter Vendor Show and Science Talk Kick-off

 

Dennis France -  The Novartis Institute for Biomedical Research "Introduction"

Paul Domanico -  Glaxo Wellcome, Inc. -  "Evaluating Assay Technologies for Supporting Lead Discovery"

Bill Janzen -  Sphinx Pharmaceuticals -  "High Throughput Screening: An Industry Overview"

 

October 1999 Fall Science and Technology Symposium

 

Dale Christensen, PhD - Novalon Pharmaceutical Corp.
"Molecular Braille: A Novel Technology for Identification and Characterization of Compounds that Modulate Receptor Function" - (Abstract unavailable)

Jorge Daniel Cortese, MD - UNC School of Medicine
"Fluorescence Correlation Spectroscopy: Inspecting molecules and their interactions at HTS speed" -  (Abstract unavailable)

Yan Zhang-Klompus, PhD - LJL BioSystems
"Homogeneous, High Throughput Detection of SNPs Using Fluorescent Technologies" - (Abstract unavailable)

Jeffrey A. Heroux, PhD - IGEN International Inc
"The Use of ORIGEN Technology as a Detection Platform in the Drug Discovery Process" - (Abstract unavailable)

                                  Posters - October 1999

Vendors:
BeckmanCoulter
Tecan
Bohdan
Kendro Laboratory Products
Labsystems
Oxford Molecular
Luminex Corporation
Gilson, Inc.
Tomtec
IDBS
PE Biosystems Tropix Division
Argonaut Technologies
Alcott Chromatography Inc.
QIAGEN
LJL BioSystems
Robbins Scientific
Cellomics, Inc.

Non-vendors:
Ormand, James  - Glaxo Wellcome
"GDO/IS Automation and Chromatography Robotics Team"

Bruner, Jimmy - Glaxo Wellcome
"Expanding the Capabilities of the Zymark BenchMate"

Birkemo, Larry - Glaxo Wellcome
"Automated in vitro Assessment of Human CYP 3A and 2D6 Inhibition Using a Microsoft Excel® -Based User Interface and a Gilson 215 Sample Processor"

David Igo - Glaxo Wellcome
"Automating Solubility Determinations Within Pharmaceutical Development Using a Gilson Liquid Handler"

 

Spring 2000 Science and Technology Symposium

 

Mario H. Geysen, PhD -  Glaxo Wellcome  - "A Highly Automated Approach to the Synthesis and Analysis of Bead-Based Combinatorial Chemical Libraries"

Patrick Kiser, PhD -  ChemCodes - "A Combinatorial Approach to Reaction Identification and Quantitation"
 

Steve Sundberg, Caliper Technologies Corporation - "Microchip-Based Systems for High Throughput Screening"
 

Dwight Walker, PhD - Glaxo Wellcome - "Application of Chemical Reaction Screening at Glaxo Wellcome Inc.

 

October 2000 Fall Science and Technology Symposium

 

Fei Ye, PhD - Glaxo Wellcome, Inc
"Microsphere-Based Readout Technology for High Throughput SNP Analysis"

Michael Pettigrew - ORCHID Biotech
"A Discussion of a Fully Automated High Throughput Genotyping System, Using Single Base Primer Extension Biochemistry"

H. Holden Thorpe, PhD - University of North Carolina, Chapel Hill
"Redox Reactions of Nucleobases: A platform for High-Throughput Expression Analysis"

Jeff Woessner, PhD - Paradigm Genetics
"High Throughput Processes for Determining Gene Function in Plants and Fungi"

Yiwa He, PhD - GlaxoWellcome - "An Automation Approach for High Throughput SNPs Analysis at GW"

 

Posters October 2000                                                                                                                                      

Optimizing Production Of Serially Diluted Compounds And Distribution To Multiple Targets
Cole O. Harris and Stephanie L. Schweiker, GlaxoWellcome, Inc.

Process Improvements: Increasing the Throughput and Efficiency of the Liquid Handling Group at Glaxo Wellcome
Jimmy Ballinger, Heather Judy, Brandy Lloyd, and Donald Lyerly, Glaxo Wellcome Inc., Research Triangle Park, NC

Understanding Liquid Handling on a Packard Multiprobe II
James Ormand, Jimmy Bruner, and Larry Birkemo, Glaxo Wellcome Inc., Research Triangle Park, N.C.

Just-in-Time Compound Delivery to Multiple Kinase Targets for Concurrent Specificity Screening
Brent T. Butler, Cole O. Harris, Stephanie L. Schweiker and Edgar R. Wood, Molecular Biochemistry Department, Glaxo Wellcome Inc. Research Triangle Park

Automated Plasma Protein Binding Screen: Implementation on a Tecan Genesis and Zymark RapidPlate
Kelly Jordan, Jimmy Bruner, Cosette Serabjit-singh and Stephen A. Wring, Glaxo Wellcome Inc. Research Triangle Park, NC

Evaluation of "Triage" Mixing for High Throughput Screening
Kiyomi Carter2, Julia M. Heerding, Amy D. Hilton2 and William P. Janzen2
Departments of Lead Generation Chemistry1 and Lead Generation Technology2, Sphinx Pharmaceuticals, A Division of Eli Lilly and Company

Development and Validation of a High Throughput Turbidimetric Solubility Assay
Kimberly Pratt-Basden, Tami Prager, Gail Wyatt, and Paul A. Johnston.
Sphinx Pharmaceuticals, A Division of Eli Lilly and Company. P.O. Box 13951, Research Triangle Park, NC 27709.

Characterization of the 3-Day Caco-2 in vitro Absorption Model
Todd Levins and Paul A. Johnston
Sphinx Pharmaceuticals, A Division of Eli Lilly and Company. P.O. Box 13951, Research Triangle Park, NC 27709.

 

Vendor Posters:

Automated Genotyping using the Tecan Genesis Robotic Workstation
Samir M. Dandekar, The Technology Integration Group, LLC

BRET2 - A Novel Technology for the Measurement of Signal Transduction Pathways in Intact Cells
Packard Instruments

PW384 - A Novel System for Automated Cell Washing in 384-Well Plate Formats
Tecan US

New Techniques in Software Data Management
Jim Lepesko, NuGenesis Technologies

                          

July 2001 Summer Science and Technology Symposium

Joe Trask, PhD - Eli Lilly & Company - Sphinx Laboratories (Title and Abstract unavailable)

Don Awrey , PhD - Integrative Proteomics (Title and Abstract unavailable)

Andrea Sefler, PhD - GlaxoSmithKline (Title and Abstract unavailable)

Jay Gill, PhD - GlaxoSmithKline (Title and Abstract unavailable)

                                                           

July 2002 Summer Science and Technology Symposium

 

Rodney Turner - Fluidigm Corp - "How Will Microfluidics Using Integral Pumps and Valves Radically Change Your Science?"

Paul Bernasconi - Amphora Discovery Corp - "Microfluidics in the Real World"

Jennings Worley - Amphora Discovery Corp - "IonWorksTMHT - A New High Throughput Electrophysiology Measurement Platform"

Mark A. Paulik - GlaxoSmithKline - "Thermogenic Imaging- Novel in vitro and in vivo Assay Platforms for Measuring Metabolic Changes Associated with Drug Therapies"

Debbie Moon - Caliper LS - "Protein Kinase Assay Development using Caliper LabChip® Systems"

 

October 2003 Fall Science and Technology Symposium

 

Sean Graves, PhD - BIOPHILE   "Automation of Ultra Low Temperature Samples, an Effective Solution."

Scot Huber, PhD - Scynexis -  "A MEDCHEM-FACTORY: Integrating High-Throughput Synthesis and Purification to Efficiently Deliver High-Quality Compounds for Discovery."

William  Vannah, PhD - Protedyne -  "Software architecture of a lightweight, XML -based robot -LIMS interface." 

Fang Yi, PhD - Department of Biochemistry and Biophysics, UNC at Chapel Hill -  "High Throughput Precise Protein Stability Measurements Facilitated By Robotics."  

 

October 2004 Fall Science and Technology Symposium

 

Keith Koutsky - Icoria "Image Analysis in an HTS Pipeline"

Morteza Khaledi, PhD - North Carolina State University - Raleigh, NC       "Advances in Electrokinetic Chromatography: Prospects for Prediction of Two-Dimensional Peptide Maps and High Throughput Drug Screening"

Amy Siu, PhD - GlaxoSmithKline -   "Automated Cell-based Assay Optimization by Design of Experiment" 

Rick Saul, PhD - Axo Diagnostics -  "Design and Development of an Automated, Mass Spec-based Clinical Diagnostic System for the Detection of Ovarian Cancer"

 

November 2004 SERMACS - Southeastern Regional Meeting of the American Chemical Society

 

SERMACS November 2004 -  LRIG SouthEast Chapter Invited Speakers

 

Pre-register for the LRIG SE 2007 Technology Exhibition on May 10 at the RTP Sheraton here!

 

 

 

 

 

 

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Copyright © 1999 Laboratory Robotics Interest Group SouthEast Chapter.Last modified: 05/20/2008
 For problems or questions regarding this web contact
[Scott Depee].
 Last updated: 05/20/08.