Academia and Industry Working Together to Ease the Drug Discovery Bottleneck
The aim of this workshop was to gain a better understanding of the changing landscape at the pharma-academia/NIH interface, the role of academia/NIH in translational research, developing a win-win scenario for technology transfer, and to explore opportunities for close collaboration between Pharma and Academia/NIH.
Meeting Sponsors:
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Date: Thursday, October 15, 2009
Event: Pre-meeting Luncheon hosted by Caliper Life Sciences
*this is a seperate event hosted by Caliper and requires seperate registration
Location: The Congress Plaza Hotel, 520 S. Michigan Ave, Chicago, IL
Event:LRIG Evening Reception 5:30 PM - 8:30 PM
Location: Roosevelt University, 430 S. Michigan Ave, Chicago, IL
Date: Friday, October 16, 2009, 8:30 AM - 4:30 PM
Location: Roosevelt University, 430 S. Michigan Ave, Chicago, IL
Program Outline:
Chairperson: Rathnam Chaguturu, Director, HTS Laboratory, University of Kansas
| Morning Session | Government-University-Industry Partnership to Ease Drug Discovery Bottleneck. Session Chair, Michael Hoffmann | |
| 8:00 | Registration | Continental Breakfast - Vendor Exhibits Open |
| 8:30 | Bob Cline Midwest LRIG President |
Welcome |
| 8:35 | Rathnam Chaguturu Conference Chair |
Opening Remarks |
| 8:45 | Wei Zhang NIH, Keynote Speaker |
Molecular Library Screen at NIH Facilitates New Drug Discovery and Development |
| 9:15 | Roger Bosse PerkinElmer |
Bridging the Gap between Research and Development Through Synergistic / Academic Collaborations |
| 9:45 | Jim Baxendale KU Ctr for Technology |
The Expanding Role of Academic Technology Transfer Offices in University/Industry Collaborations |
| 10:15 | Vendor Spotlight | |
| 10:30 | Morning Break with Refreshments, Vendor Exhibits Open | |
| 10:45 | John Watson Promega |
Using Bioluminescent Technologies to Screen for Small Molecule Modulators of Cell Signaling Pathways |
| 11:15 | Karuppaiah Kannan AVEO Pharmaceuticals |
Translational Pharmacogenomics in Drug Discovery and Validation |
| 11:45 | Jeff Tishler IDBS |
Compound to Candidate A Complete Drug Discovery Data Management Solution |
| 12:15 | Panel Discussion | Moderator: John Watson, Promega Finding a Common Ground to Forge a Lasting Partnership.The panelists are Jim Baxendale (Technology commercialization Director at KU), Wei Zhang (NIH-NCGC), Roger Bosse (Perkin Elmer), Karuppiah Kannan (Aveo Pharmaceuticals) and Jeff Tishler (IDBS). |
| 12:45 | Lunch | Vendor Sessions; Vendor Presentations; Poster Viewing |
| Afternoon Session | Role of Academic Screening Centers in Drug Discovery. Session Chair, Derek Hook | |
| 1:45 | Michael Hoffmann U of Wisconsin |
Six Years of Probe Discovery at UW-Madison: Responding to the Varied and Evolving Needs of Academic Labs for HTS, MOA Assays, Virtual Screening and Synthetic Chemistry |
| 2:15 | Martha Larsen U of Michigan |
Turning the Bottleneck into a Funnel: Academics Tackle Drug Discovery |
| 2:45 | Afternoon Break with Refreshments, Vendor Exhibits Open | |
| 3:00 | Sam Bettis U of Chicago |
Creating a High-Throughput Cellular Screening Center to Serve Chicago Academia |
| 3:30 | Michael Walters U of Minesota |
Designed for Success: Medicinal Chemistry Support in Drug Discovery and Development |
| 4:00 | Chi-Hao Luan Northwestern University |
High Throughput Biology, Drug Discovery, and Translational Research in Academic Institutions |
| 4:30 | Panel Discussion | Moderator: Martha Larsen, University of Michigan
Target and Probe Discovery in Academia: Is it a Panacea or a Pandora’s Box? The panelists are all HTS Directors: Derek Hook, Michael Hoffmann, Chi-Hao Luan, Michael Walters, Sam Bettis, Rathnam Chaguturu. |
About the Program Chairperson
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Rathnam Chaguturu is the Director of the High Throughput Screening Laboratory at the University of Kansas and has more than 30 years of experience in new lead discovery and development, executing high throughput screens and managing hit to lead projects. He joined Rutgers University in 1976 as an Assistant Professor of Biochemistry, and later moved to Dow Chemical Company-Central Research Laboratories as a Project Leader. At Dow, Rathnam instituted the first principles of chemical library screening for new lead discovery, and developed tools for mining in-house chemical archives. Rathnam joined Sierra Sciences as Director of Drug Discovery in 2006 after a 22-year outstanding career at FMC Corporation where he led discovery research efforts focused on ion channel, receptor, enzyme and cell-based targets, and instrumental in designing the industry-first Zymark robotic screening platform for new lead discovery. As a representative of FMC, he was one of the founding members of the Society for Biomolecular Sciences. Dr. Chaguturu has authored over 45 research publications including reviews and book chapters, and holds 11 US patents.