PFIZER - Senior Principal Research Scientist, Biology - Vaccines Research

[Christina Espiritu]

Please apply directly via Pfizer's Career Site - apply online at www.pfizercareers.com
Job ID: 961741

POSITION SUMMARY
The Ligand-Binding Immunoassay Team generates immunoassay data in a high-throughput setting under cGLP regulations to support Pfizer vaccine programs. This position participates hands-on and oversees projects involving development and validation of new/existing automated methods performed on various robotic platforms to support immunoassays that are performed under cGLP. The incumbent is responsible for the transition and successful integration of new and updated robotic methods from initial development through validation and release for daily, high-throughput testing. The incumbent is responsible for process improvements and for any laboratory process changes that are required to accommodate equipment software/hardware updates and or modifications to the supporting data systems.

POSITION RESPONSIBILITIES
1. Responsible for the successful, seamless integration of various laboratory processes to maintain efficient high-throughput testing and to achieve high-quality results. Oversees and participates hands-on with projects involving the development and validation of new automated methods and processes on various new and existing robotic platforms to support immunoassays that are performed under cGLP.

2. Works directly with support staff to manage the improvement of various laboratory process to accommodate any required changes in new and existing data systems. Investigates and makes recommendations regarding new technologies and platforms.

3. Works with assay-transfer leaders to manage the automation of methods being transferred from the assay development groups into the clinical testing laboratories.

4. Authors, reviews and approves various reports and Standard Operating Procedures that are related to new and existing robotic methods.

5. Supervise and manage the daily activity of technical laboratory personnel, including training on procedures or use of equipment.

6. Present experimental results at group meetings, project meetings and department meetings.

7. Satisfactorily completes all cGLP training and safety training in conformance with Departmental requirements.

8. Where applicable, performs job responsibilities in compliance with cGLP and Pfizer requirements.


EDUCATION AND EXPERIENCE
A Ph.D. degree in a scientific discipline such as microbiology/immunology and minimum 10 years of pharmaceutical/biotechnology experience is necessary. A minor in computer science or related field is desirable. A strong background in cGLP regulations, immunology and/or microbiology, immunoassay development, robotic method development and relational databases is essential. Excellent verbal and written communication skills is required.

1. Extensive knowledge of relational databases and various liquid-handling robotic systems.

2. Practical knowledge of immunology/microbiology and immunoassay development and validation.

3. Ability to analyze and interpret scientific data, and effectively communicate findings to peers and colleagues.

4. Proficiency with personal computers including word processing, spreadsheets, and relevant scientific and LIMS software.

5. Ability to manage multiple projects and lead diverse project teams is essential.

Technical Skills
A Ph.D. degree in a scientific discipline such as microbiology/immunology and minimum 10 years of pharmaceutical/biotechnology experience is necessary. A minor in computer science or related field is desirable. A strong background in cGLP regulations, immunology and/or microbiology, immunoassay development, robotic method development and relational databases is essential. Excellent verbal and written communication skills is required.

1. Extensive knowledge of relational databases and various liquid-handling robotic systems.

2. Practical knowledge of immunology/microbiology and immunoassay development and validation.

3. Ability to analyze and interpret scientific data, and effectively communicate findings to peers and colleagues.

4. Proficiency with personal computers including word processing, spreadsheets, and relevant scientific and LIMS software.

5. Ability to manage multiple projects and lead diverse project teams is essential.