
LRIG Southeast Chapter
LRIG
SouthEast Presentations
June 7, 1999
LRIG SouthEast Chapter Vendor Show and Science
Talk Kick-off
Dennis France - The Novartis
Institute for Biomedical Research "Introduction"
Paul Domanico - Glaxo Wellcome, Inc. - "Evaluating Assay Technologies for
Supporting Lead Discovery"
Bill Janzen - Sphinx Pharmaceuticals - "High Throughput
Screening: An Industry Overview"
October 1999 Fall Science and
Technology Symposium
Dale Christensen, PhD -
Novalon Pharmaceutical Corp.
"Molecular Braille: A Novel Technology for Identification and
Characterization of Compounds that Modulate Receptor Function" -
(Abstract unavailable)
Jorge Daniel Cortese, MD -
UNC School of Medicine
"Fluorescence Correlation Spectroscopy: Inspecting molecules and their interactions at HTS
speed" - (Abstract unavailable)
Yan Zhang-Klompus, PhD -
LJL BioSystems
"Homogeneous, High Throughput Detection of SNPs Using Fluorescent
Technologies" - (Abstract unavailable)
Jeffrey A. Heroux, PhD -
IGEN International Inc
"The Use of ORIGEN Technology as a Detection Platform in the Drug Discovery Process"
- (Abstract unavailable)
Posters - October 1999
Vendors:
BeckmanCoulter
Tecan
Bohdan
Kendro Laboratory Products
Labsystems
Oxford Molecular
Luminex Corporation
Gilson, Inc.
Tomtec
IDBS
PE Biosystems Tropix Division
Argonaut Technologies
Alcott Chromatography Inc.
QIAGEN
LJL BioSystems
Robbins Scientific
Cellomics, Inc.
Non-vendors:
Ormand, James -
Glaxo Wellcome
"GDO/IS Automation and Chromatography Robotics Team"
Bruner, Jimmy -
Glaxo Wellcome
"Expanding the Capabilities of the Zymark BenchMate"
Birkemo, Larry -
Glaxo Wellcome
"Automated in vitro Assessment of Human CYP 3A and 2D6 Inhibition Using a Microsoft Excel®
-Based User Interface and a Gilson 215 Sample Processor"
David Igo -
Glaxo Wellcome
"Automating Solubility Determinations Within Pharmaceutical Development Using a Gilson
Liquid Handler"
Spring 2000
Science and Technology Symposium
Mario H. Geysen, PhD - Glaxo Wellcome
- "A Highly
Automated Approach to the Synthesis and Analysis of Bead-Based Combinatorial Chemical
Libraries"
Patrick Kiser, PhD - ChemCodes
- "A
Combinatorial Approach to Reaction Identification and Quantitation"
Steve Sundberg, Caliper Technologies Corporation
- "Microchip-Based
Systems for High Throughput Screening"
Dwight Walker, PhD - Glaxo Wellcome
- "Application
of Chemical Reaction Screening at Glaxo Wellcome Inc.
October 2000 Fall Science and
Technology Symposium
Fei Ye, PhD -
Glaxo Wellcome, Inc
"Microsphere-Based Readout Technology for
High Throughput SNP Analysis"
Michael Pettigrew -
ORCHID Biotech
"A
Discussion of a Fully Automated High Throughput Genotyping System, Using Single Base
Primer Extension Biochemistry"
H. Holden Thorpe, PhD -
University of North Carolina, Chapel Hill
"Redox Reactions of
Nucleobases: A platform for High-Throughput Expression Analysis"
Jeff Woessner, PhD -
Paradigm Genetics
"High Throughput Processes for Determining Gene Function in Plants and Fungi"
Yiwa He, PhD -
GlaxoWellcome -
"An Automation Approach for High Throughput SNPs Analysis at
GW"
Posters October 2000
Optimizing Production Of Serially Diluted Compounds And
Distribution To Multiple Targets
Cole O. Harris and Stephanie L. Schweiker, GlaxoWellcome, Inc.
Process Improvements: Increasing the Throughput and Efficiency
of the Liquid Handling Group at Glaxo Wellcome
Jimmy Ballinger, Heather Judy, Brandy Lloyd, and Donald Lyerly,
Glaxo Wellcome Inc., Research Triangle Park, NC
Understanding Liquid Handling on a Packard Multiprobe II
James Ormand, Jimmy Bruner, and Larry Birkemo, Glaxo Wellcome
Inc., Research Triangle Park, N.C.
Just-in-Time Compound Delivery to Multiple Kinase Targets for
Concurrent Specificity Screening
Brent T. Butler, Cole O. Harris, Stephanie L. Schweiker and
Edgar R. Wood, Molecular Biochemistry Department, Glaxo Wellcome
Inc. Research Triangle Park
Automated Plasma Protein Binding Screen: Implementation on a
Tecan Genesis and Zymark RapidPlate
Kelly Jordan, Jimmy Bruner, Cosette Serabjit-singh and Stephen
A. Wring, Glaxo Wellcome Inc. Research Triangle Park, NC
Evaluation of "Triage" Mixing for High Throughput Screening
Kiyomi Carter2, Julia M. Heerding, Amy D. Hilton2
and William P. Janzen2
Departments of Lead Generation Chemistry1 and Lead
Generation Technology2, Sphinx Pharmaceuticals, A
Division of Eli Lilly and Company
Development and Validation of a High Throughput Turbidimetric
Solubility Assay
Kimberly Pratt-Basden, Tami Prager, Gail Wyatt, and Paul A.
Johnston.
Sphinx Pharmaceuticals, A Division of Eli Lilly and Company. P.O.
Box 13951, Research Triangle Park, NC 27709.
Characterization of the 3-Day Caco-2 in vitro Absorption Model
Todd Levins and Paul A. Johnston
Sphinx Pharmaceuticals, A Division of Eli Lilly and Company. P.O.
Box 13951, Research Triangle Park, NC 27709.
Vendor Posters:
Automated Genotyping using the Tecan Genesis Robotic
Workstation
Samir M. Dandekar, The Technology Integration Group, LLC
BRET2 - A Novel Technology for the Measurement of Signal
Transduction Pathways in Intact Cells
Packard Instruments
PW384 - A Novel System for Automated Cell Washing in 384-Well
Plate Formats
Tecan US
New Techniques in Software Data Management
Jim Lepesko, NuGenesis Technologies
July 2001 Summer
Science and Technology Symposium
Joe Trask, PhD - Eli Lilly & Company - Sphinx Laboratories
(Title and Abstract unavailable)
Don Awrey , PhD - Integrative Proteomics (Title and Abstract
unavailable)
Andrea Sefler, PhD - GlaxoSmithKline (Title and Abstract
unavailable)
Jay Gill, PhD - GlaxoSmithKline (Title and Abstract
unavailable)
July 2002 Summer
Science and Technology Symposium
Rodney Turner -
Fluidigm
Corp -
"How Will Microfluidics Using Integral
Pumps and Valves Radically Change Your Science?"
Paul Bernasconi - Amphora Discovery Corp
-
"Microfluidics in the Real World"
Jennings Worley - Amphora Discovery Corp
-
"IonWorksTMHT - A New High Throughput Electrophysiology
Measurement Platform"
Mark A. Paulik - GlaxoSmithKline -
"Thermogenic Imaging- Novel in vitro and in vivo
Assay Platforms for Measuring Metabolic Changes Associated with Drug Therapies"
Debbie Moon - Caliper LS -
"Protein Kinase Assay Development using Caliper LabChip® Systems"
October 2003 Fall
Science and Technology Symposium
Sean
Graves, PhD - BIOPHILE "Automation
of Ultra Low Temperature Samples, an Effective Solution."
Scot Huber, PhD - Scynexis
- "A
MEDCHEM-FACTORY: Integrating High-Throughput Synthesis and Purification to Efficiently
Deliver High-Quality Compounds for Discovery."
William Vannah,
PhD - Protedyne - "Software
architecture of a lightweight, XML -based robot -LIMS interface."
Fang
Yi, PhD - Department of Biochemistry and Biophysics, UNC at Chapel Hill
- "High Throughput Precise Protein Stability
Measurements Facilitated By Robotics."
October 2004 Fall
Science and Technology Symposium
Keith Koutsky - Icoria
-
"Image Analysis in an HTS
Pipeline"
Morteza Khaledi, PhD - North Carolina State University - Raleigh, NC
"Advances in Electrokinetic
Chromatography: Prospects for Prediction of Two-Dimensional Peptide Maps and
High Throughput Drug Screening"
Amy Siu, PhD -
GlaxoSmithKline -
"Automated Cell-based Assay Optimization by Design of Experiment"
Rick
Saul, PhD - Axo Diagnostics -
"Design and Development of an Automated, Mass Spec-based Clinical Diagnostic
System for the Detection of Ovarian Cancer"
November 2004 SERMACS
- Southeastern Regional Meeting of the American Chemical Society
SERMACS November 2004 -
LRIG SouthEast Chapter
Invited Speakers
Pre-register for the LRIG SE 2007
Technology Exhibition on May 10 at the RTP Sheraton here!
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